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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PI4K2A
All Species:
37.58
Human Site:
Y402
Identified Species:
68.89
UniProt:
Q9BTU6
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BTU6
NP_060895.1
479
54022
Y402
K
D
L
E
E
D
L
Y
E
L
F
K
K
D
P
Chimpanzee
Pan troglodytes
XP_001164880
481
54254
Y404
K
D
L
E
E
D
L
Y
E
L
F
K
K
D
P
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_543953
484
54388
Y407
K
D
L
E
E
D
L
Y
E
L
F
K
K
D
P
Cat
Felis silvestris
Mouse
Mus musculus
Q2TBE6
479
54239
Y402
K
D
L
E
E
D
L
Y
E
L
F
K
R
D
P
Rat
Rattus norvegicus
Q99M64
478
54286
Y401
K
D
L
E
E
D
L
Y
E
L
F
K
K
D
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513782
411
46894
Y328
Q
D
L
C
E
D
L
Y
E
L
F
K
T
D
K
Chicken
Gallus gallus
Q5ZIK0
479
53903
H398
Q
D
L
C
E
D
L
H
E
L
F
K
T
D
K
Frog
Xenopus laevis
Q08B31
469
53187
Y392
K
D
L
E
E
D
L
Y
E
L
F
K
K
D
Q
Zebra Danio
Brachydanio rerio
Q6PE18
447
51424
Y370
K
D
L
E
E
D
L
Y
E
L
F
K
K
D
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120474
466
53705
Y385
Q
D
L
C
D
D
L
Y
Q
L
F
K
Q
D
K
Nematode Worm
Caenorhab. elegans
NP_508849
593
66195
R452
R
E
L
C
G
D
L
R
R
V
F
K
N
D
K
Sea Urchin
Strong. purpuratus
XP_801707
506
57844
Y422
E
E
L
C
T
E
L
Y
S
L
F
G
E
D
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P42951
607
70198
L471
E
E
S
Y
Q
E
F
L
A
L
F
S
R
D
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.9
N.A.
97.5
N.A.
95.4
94.9
N.A.
59.7
60.1
78
76.6
N.A.
N.A.
55.5
40.2
52.3
Protein Similarity:
100
98.3
N.A.
98.1
N.A.
97.6
96.8
N.A.
70.3
72.4
83.9
83.7
N.A.
N.A.
69.9
50.2
66.8
P-Site Identity:
100
100
N.A.
100
N.A.
93.3
100
N.A.
73.3
66.6
93.3
100
N.A.
N.A.
60
40
40
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
80
80
93.3
100
N.A.
N.A.
86.6
60
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
41.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% A
% Cys:
0
0
0
39
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
77
0
0
8
85
0
0
0
0
0
0
0
100
0
% D
% Glu:
16
24
0
54
70
16
0
0
70
0
0
0
8
0
0
% E
% Phe:
0
0
0
0
0
0
8
0
0
0
100
0
0
0
0
% F
% Gly:
0
0
0
0
8
0
0
0
0
0
0
8
0
0
0
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
54
0
0
0
0
0
0
0
0
0
0
85
47
0
39
% K
% Leu:
0
0
93
0
0
0
93
8
0
93
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
47
% P
% Gln:
24
0
0
0
8
0
0
0
8
0
0
0
8
0
16
% Q
% Arg:
8
0
0
0
0
0
0
8
8
0
0
0
16
0
0
% R
% Ser:
0
0
8
0
0
0
0
0
8
0
0
8
0
0
0
% S
% Thr:
0
0
0
0
8
0
0
0
0
0
0
0
16
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
77
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _